產(chǎn)品詳情

  • 產(chǎn)品名稱：Neratinib

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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Neratinib
詳情介紹：
Characteristics Cell-permeable. A second-generation inhibitor of the ErbB family of receptor kinases. Neratinib acts as an irreversible inhibitor of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER-2) tyrosine kinases by targeting a cysteine residue in the ATP- of the receptor. It inhibits the proliferation of HER-2 overexpressing human breast cancer cell lines and EGFR-dependent cells in vitro.
Purity ≥ 98?% by HPLC
Chemical Name HKI-272
Formula C??H??ClN?O?
Permeability Cell-permeable
Molecular Weight 557.04 g/mol
CAS-No 698387-09-6
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 24 months
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