產(chǎn)品詳情

  • 產(chǎn)品名稱：ICG-001

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
ICG-001
詳情介紹：
Characteristics A specific inhibitor of Wnt/beta-catenin signaling pathway. It down-regulates beta-catenin/T cell factor signaling by specifically binding to cyclic AMP response element-binding protein (CBP). ICG-001 selectively induces apoptosis in transformed cells but not in normal colon cells, reduces in vitro growth of colon carcinoma cells, and is efficacious in the Min mouse and nude mouse xenograft models of colon cancer.
Purity ≥ 98?% by HPLC
Chemical Name (6S,9aS)-Hexahydro-6-[(4-hydroxyphe-nyl)methyl]-8-(1-naphthalenylmethyl)-4,7-dioxo-N-(-phenylmethyl)-2H-pyrazino[1,2-a]pyrimidine-1(6H)-c-arboxamide
Formula C??H??N?O?
Permeability Cell-permeable
Molecular Weight 548.63 g/mol
CAS-No 847591-62-2
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 24 months
Supplier Images
image for ICG-001 (ABIN1685569) ICG-001