產(chǎn)品詳情
  • 產(chǎn)品名稱(chēng):GSK-690693

  • 產(chǎn)品型號(hào):
  • 產(chǎn)品廠商:Biovision
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簡(jiǎn)單介紹:
GSK-690693
詳情介紹:
Characteristics An ATP-competitive pan-Akt kinase inhibitor. Inhibits Akt kinase isoforms 1, 2, 3 with IC50values of 2, 13, and 9 nM, respectively. Inhibited proliferation and induced apoptosis in a subset of tumor cells with potency consistent with intracellular inhibition of Akt kinase activity.
Purity ≥ 98?% by HPLC
Chemical Name 4-[2-(4-Amino-1,2,5-oxadiazol-3-yl)--1-ethyl-7-[(3S)-3-piperidinylmethoxy)-1H-imidazo[-4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol
Formula C??H??N?O?
Permeability Cell-permeable
Molecular Weight 425.48 g/mol
CAS-No 937174-76-0
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 24 months
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