產(chǎn)品詳情
簡單介紹:
(±)-Blebbistatin
詳情介紹:
Characteristics | Cell-permeable. A selective inhibitor of non-muscle myosin II ATPases. It rapidly and reversibly inhibits Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB for several species (IC50= 0.5-5.0 μM), while weakly inhibiting smooth muscle myosin (IC50= 80 μM). Through these effects, blebbistatin reversibly blocks apoptosis-related bleb formation, directed cell migration and cytokinesis in vertebrate cells. |
Purity | ≥ 98?% by HPLC |
Chemical Name | (±)-1,?2,?3,?3a-?tetrahydro-?3a-?hydroxy-?6-?methyl-?1-?phenyl-?4H-?pyrrolo[2,?3-?b]quinolin-?4-?one |
Formula | C??H??N?O? |
Permeability | Cell-permeable |
Molecular Weight | 292.34 g/mol |
CAS-No | 674289-55-5 |
Restrictions | For Research Use only |
Format | Solid |
Handling Advice | Protect from light and air |
Storage | -20 °C |
Expiry Date | 36 months |
Supplier Images |
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