產(chǎn)品詳情

  • 產(chǎn)品名稱：Borrelidin

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡單介紹：
Borrelidin
詳情介紹：
Characteristics A macrolide antibiotic isolated from Streptomyces sp. An antiangiogenic (IC50= 0.8 nM) agent. Bacterial and eukaryal threonyl-tRNA synthetase (THrRS) inhibitor. Induces the collapse of formed capillary tubes in a dose-dependent fashion. In HUVECs, the capillary tube collapsing activity is mediated by the activation of caspases-3 and -8 and induction of apoptosis. Also acts as a CDK inhibitor.
Purity ≥ 98?% by HPLC
Chemical Name Treponemycin; U 78548; C2989
Formula C??H??NO?
Permeability Cell-permeable
Molecular Weight 489.64 g/mol
CAS-No 7184-60-3
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and moisture
Storage -20 °C
Expiry Date 36 months
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