產(chǎn)品詳情

  • 產(chǎn)品名稱：OSU-03012

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡單介紹：
OSU-03012
詳情介紹：
Characteristics A novel celecoxib derivative, that acts as a potent inhibitor of 3-phosphoinositide-dependent kinase-1 (PDK1) activity (IC50 = 5 μM for recombinant PDK1). It displays anti-cancer activity in a COX-2-independent manner via inhibition of the phosphatidyl inositol-3-kinase(PI3K)/Akt pathway. OSU03012 is a potent inhibitor of tumor cell growth with an average inhibitory concentration of 1.1 μM across a panel of 60 cancer cell lines.
Purity ≥ 98?% by HPLC
Chemical Name 2-amino-N-(4-(5-(phenanthren-2-yl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)phenyl)acetamide; OSU03012; AR-12
Formula C??H??F?N?O
Permeability Cell-permeable
Molecular Weight 460.45 g/mol
CAS-No 742112-33-0
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 36 months
Supplier Images
image for OSU-03012 (ABIN1685608) OSU-03012