產(chǎn)品詳情
  • 產(chǎn)品名稱:(-)-JQ1

  • 產(chǎn)品型號(hào):
  • 產(chǎn)品廠商:Biovision
  • 產(chǎn)品文檔:
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簡(jiǎn)單介紹:
(-)-JQ1
詳情介紹:
Characteristics Cell-permeable. A useful negative control for the BET bromodomain inhibitor (+)-JQ1 (ABIN1304030). (-)-JQ1 enantiomer has no appreciable affinity to BET bromodomains, whereas enantiomerically pure (+)-JQ1 binds to BRD4 bromodomains 1 and 2 with Kd values of ca. 50 and 90 nM, respectively.
Purity ≥ 98?% by HPLC
Chemical Name t-Butyl-2-((6R)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate
Formula C??H??ClN?O?S
Permeability Cell-permeable
Molecular Weight 456.99 g/mol
CAS-No 1268524-71-5
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and air
Storage -20 °C
Expiry Date 36 months
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