產(chǎn)品詳情

  • 產(chǎn)品名稱：HPI-1

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡單介紹：
HPI-1
詳情介紹：
Characteristics HPI-1 is a Hedgehog pathway inhibitor acting downstream of Smo and independently of PKA, PI3K and MAPK. It can suppress Hh pathway activation induced by loss of Su(fu) or Gli overexpression. Inhibits both endogenous and exogenous Gli1/Gli2 activity. IC50's range from 0.2 to 6 μM for various cell-based assays.
Purity ≥ 98?% by TLC
Chemical Name 2-Methoxyethyl 1,4,5,6,7,8-hexahydro-4-(3-hydroxyphenyl)-7-(-(2-methoxyphenyl)-2-methyl-5-oxo-3-quinolinecarboxylate
Formula C??H??NO? ? XH?O
Permeability Cell-permeable
Molecular Weight 463.52 g/mol
CAS-No 599150-20-6
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and air
Storage -20 °C
Expiry Date 36 months
Supplier Images
image for HPI-1 (ABIN1685833) HPI-1