產(chǎn)品詳情

  • 產(chǎn)品名稱：GSK-2126458

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡單介紹：
GSK-2126458
詳情介紹：
Characteristics Cell-permeable. A highly potent, pan phosphoinositide 3-kinase (PI 3-K) family kinase inhibitor with biochemical Ki,'s of 0.019 nM (PI 3-Kbeta), 0.13 nM (PI 3-Kbeta), 0.024 nM (PI 3-Kdelta), 0.06 nM (PI 3-Kalpha), 0.18 nM (mTORC1), and 0.3 nM (mTORC2). In vivo, GSK2126458 displays anti-tumor activity in both pharmacodynamic and tumor growth efficacy models.
Purity ≥ 98?% by HPLC
Chemical Name 2,4-Difluoro-N-{2-(methyloxy)-5-[4-(4-pyridazinyl)-6-quinolinyl]-3-pyridinyl}benzenesulfonamide
Formula C??H??F?N?O?S
Permeability Cell-permeable
Molecular Weight 505.5 g/mol
CAS-No 1086062-66-9
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and air
Storage -20 °C
Expiry Date 48 months
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