產(chǎn)品詳情

  • 產(chǎn)品名稱：Phlorizin

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：Biovision
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Phlorizin
詳情介紹：
Characteristics Phlorizin is a competitive inhibitor of SGLT1 (sodium glucose co-transporter 1) and SGLT2 (sodium glucose co-transporter 2), this reduces renal glucose transport, lowering the amount of glucose in the blood. It competitively inhibits the initial rate of alpha-methyl-D-glucopyranoside (alpha-MDG) uptake in human COS-1 cells expressing hSGLT1 and hSGLT2 with IC50values of 400 and 65 nM, respectively. In HEK293T cells expressing human SGLT1 and SGLT2, phlorizin exhibits Ki values of 140 and 11 nM, respectively, at 37 °C.
Purity ≥ 98?%
Chemical Name 1-?[2-?(β-?D-?glucopyranosyloxy)-?4,?6-?dihydroxyphenyl]-?3-?(4-?hydroxyphenyl)-?1-?propanone; NSC 2833; Florizidin
Formula C??H??O??
Permeability Not-permeable
Molecular Weight 436.41 g/mol
CAS-No 60-81-1
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and air
Storage -20 °C
Expiry Date 36 months
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image for Phlorizin (ABIN1685843) Phlorizin