產(chǎn)品詳情

  • 產(chǎn)品名稱：BI-D1870

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
BI-D1870
詳情介紹：
Characteristics Cell-permeable. ATP-competitive inhibitor of the four isoforms of ribosomal S6 kinase (p90 RSK) (IC50's at 100 μM ATP: RSK1 = 31 nM, RSK2 = 24 nM, RSK3 = 18 nM, RSK4 = 15 nM). Does not significantly inhibit 10 other AGC kinases, and over 40 other protein kinases at 100X concentrations. In addition, BI-D1870 completely prevents PMA-induced TSC2 (a regulator of mTORC1) phosphorylation at Ser1798.
Purity ≥ 98?% by TLC
Chemical Name 2-[(3,5-Difluoro-4-hydroxyphenyl)amino]-7,8-dihydro-5,7-dimethyl-8-(3-methylbutyl)-6(5H)-pteridone
Formula C??H??F?N?O?
Permeability Cell-permeable
Molecular Weight 391.42 g/mol
CAS-No 501437-28-1
Research Area Kinases/Phosphatases
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and air
Storage -20 °C
Expiry Date 36 months
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image for BI-D1870 (ABIN629319) BI-D1870