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產(chǎn)品名稱:PuromycinDihydrochloride
產(chǎn)品型號:
產(chǎn)品廠商:Biovision
產(chǎn)品文檔:
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簡單介紹:
PuromycinDihydrochloride
詳情介紹:
Product details
Product details
Characteristics
A nucleoside antibiotic. It inhibits protein synthesis by disrupting peptide transfer on ribosomes causing premature chain termination during translation. It is a potent translational inhibitor in both prokaryotic and eukaryotic cells. Resistance to puromycin is conferred by the puromycin N-acetyl-transferase gene (pac) from Streptomyces. Puromycin has a fast mode of action, causing rapid cell death at low antibiotic concentrations. Adherent mammalian cells are sensitive to concentrations of 2 to 5 μg/mL, while cells in suspension are sensitive to concentrations as low as 0.5 to 2 μg/mL.
Purity
≥ 98?% by HPLC
Chemical Name
3'-[α-Amino-p-methoxyhydrocinnamamido]-3'-deoxy-N,N-dimethyladenosine dihydrochloride
Formula
C??H??N?O? ? 2HCl
Permeability
Not-permeable
Target details
Target details
Molecular Weight
544.43 g/mol
CAS-No
58-58-2
Research Area
Kinases/Phosphatases
Application Details
Application Details
Restrictions
For Research Use only
Handling
Handling
Format
Solid
Handling Advice
Protect from air and moisture
Storage
-20 °C
Expiry Date
24 months
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Images
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Puromycin Dihydrochloride
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Puromycin Dihydrochloride
Puromycin Dihydrochloride
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