產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：Apigenin

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Biovision
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簡(jiǎn)單介紹：
Apigenin
詳情介紹：
Purpose A naturally occurring plant flavone that displays remarkable anti-inflammatory, antioxidant and anti-carcinogenic properties.
Characteristics White solid
Molecular formular: C15H10O5
Purity ≥ 98?% by HPLC
Chemical Name 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; Chamomile; Flavone; NSC 83244; Versulin
Formula C??H??O?
Permeability Cell-permeable
Molecular Weight 270.2 g/mol
CAS-No 520-36-5
Comment

Synonyms:
5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, Chamomile, Flavone, NSC 83244, Versulin
A naturally occurring plant flavone that displays remarkable anti-inflammatory, antioxidant and anti-carcinogenic properties. It selectively inhibits casein kinase II (CK2). Apigenin inhibits CK2 activity in the renal cortex with an IC value of 30 μM to improve renal function in a rat model of glomerulonephritis. CK2 inhibition by 20 μM apigenin decreases the degradation of IB and down-regulates NF-B levels in WEHI 231 cells. At 5 μM, it is a potent inhibitor of the synthesis of the inflammatory mediators nitric oxide and prostaglandin E2, reducing inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) expression by 56 % and 64 %, respectively, in the macrophage cell line J774A.1
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
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