產(chǎn)品詳情
簡(jiǎn)單介紹:
Smad3Inhibitor,SIS3
詳情介紹:
| Purpose | A Smad3 inhibitor |
| Characteristics | A potent and selective inhibitor of Smad3 function. SIS3 selectively inhibits TGF-beta1/ALK5-induced Smad3 phosphorylation. Also inhibits the TGF-beta1 effect on type I procollagen expression at the transcriptional levels via the Smad3-. |
| Purity | ≥ 98?% by HPLC |
| Chemical Name | (2E)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-propenone hydrochloride |
| Formula | C??H??N?O? ? HCl |
| Permeability | Cell-permeable |
| Solubility | DMSO (> 20 mg/mL) |
| Molecular Weight | 489.99 g/mol |
| CAS-No | 521984-48-5 |
| Restrictions | For Research Use only |
| Format | Solid |
| Handling Advice | Protect from light and moisture |
| Storage | -20 °C |
| Expiry Date | 24 months |
| Supplier Images |
Smad3 Inhibitor, SIS3
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