產(chǎn)品詳情
簡(jiǎn)單介紹:
Triptolide
詳情介紹:
Characteristics | Triptolide, a diterpenoid triepoxyde, a purified component of a traditional Chinese medicine, inhibits transcriptional activation of NF- kappaB and downregulates the expression of various NF- kappaB-regulated genes. Displays Immunosuppressive, anti-inflammatory, anti-angiogenic and antitumor activity. A combination of TRAIL and triptolide enhance apoptosis in cholangiocarcinoma cell lines. |
Purity | ≥ 97?% by HPLC |
Chemical Name | TPL |
Formula | C??H??O? |
Permeability | Cell-permeable |
Molecular Weight | 360.4 g/mol |
CAS-No | 38748-32-2 |
Research Area | Kinases/Phosphatases |
Restrictions | For Research Use only |
Format | Solid |
Handling Advice | Protect from air and moisture |
Storage | -20 °C |
Expiry Date | 24 months |
Supplier Images |
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Product cited in: |
Villica?a, Cruz, Zurita: "The genetic depletion or the triptolide inhibition of TFIIH in p53-deficient cells induces a JNK-dependent cell death in Drosophila." in: Journal of cell science, Vol. 126, Issue Pt 11, pp. 2502-15, 2013 (PubMed).
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