產(chǎn)品詳情
簡單介紹:
Perifosine(KRX-0401)
詳情介紹:
Characteristics | Belongs to an alkylphospholipid class of antineoplastic compounds that display potent antiproliferative activity in several in vitro and in vivo human tumor models. Perifosine induces apoptotic cell death in a variety of tumor cell lines. Apoptosis is induced in a time- and dose-dependent manner in U937 and Jurkat T human leukemia cell lines but not in normal vascular endothelial cells. |
Purity | ≥ 99?% |
Chemical Name | KRX-0401 |
Formula | C??H??NO?P |
Permeability | Cell-permeable |
Molecular Weight | 462.66 g/mol |
CAS-No | 157716-52-4 |
Restrictions | For Research Use only |
Format | Solid |
Handling Advice | Protect from light and moisture |
Storage | -20 °C |
Expiry Date | 24 months |
Supplier Images |
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Product cited in: |
Maddigan, Truitt, Arsenault, Freywald, Allonby, Dean, Narendran, Xiang, Weng, Napper, Freywald: "EphB receptors trigger Akt activation and suppress Fas receptor-induced apoptosis in malignant T lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 11, pp. 5983-94, 2011 (PubMed).
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