產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：Phorbol-12-myristate13-acetate(PMA)

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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Phorbol-12-myristate13-acetate(PMA)
詳情介紹：
Characteristics This is the most commonly used phorbol ester. It binds to and activates protein kinase C, causes an extremely wide range of effects in cells and tissues and is a very potent mouse skin tumor promoter. Inhibits apoptosis induced by the Fas antigen, but induced apoptosis in HL-60 promyelocytic leukemia cells
Purity > 99?%
Chemical Name PMA, 12-O-Tetradecanoylphorbol 13-acetate,TPA, 4β,9α,12β,13α,20-Pentahydroxytiglia-1,6-dien-3-one 12-tetradecanoate 13-acetate
Formula C??H??O?
Permeability Cell-permeable
Molecular Weight 616.83 g/mol
CAS-No 16561-29-8
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light
Storage -20 °C
Expiry Date 12 months
Supplier Images
image for Phorbol-12-myristate 13-acetate (PMA) (ABIN412109) Phorbol-12-myristate 13-acetate (PMA)
Product cited in: Lu, Li, Gao, Gao, Xu, Wang, Lu, Xia, Zhou: "IL-17A, but not IL-17F, is indispensable for airway vascular remodeling induced by exaggerated Th17 cell responses in prolonged ovalbumin-challenged mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 8, pp. 3557-66, 2015 (PubMed).