產(chǎn)品詳情
簡(jiǎn)單介紹:
NuclearFactor(Erythroid-Derived2),45kDa(NFE2)(C-Term)Peptide
詳情介紹:
Blocked Antibody | anti-NFE2 antibody (Nuclear Factor (Erythroid-Derived 2), 45kDa) (C-Term) (ABIN2777229) |
Sequence | ARGEADRTLE VMRQQLAELY HDIFQHLRDE SGNSYSPEEY VLQQAADGAI |
Characteristics | This is a synthetic peptide designed for use in combination with anti-Nfe2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. |
Purification | Purified |
Background |
Nfe2 is a component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation.It binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. It requires MAFK or other small MAF proteins for binding to the NF-E2 motif. It may play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron. Alias Symbols: 45?kDa, NF-E2, p45, p45NFE2, p45nf-e2 Protein Size: 373 |
Molecular Weight | 41 kDa |
Gene ID | 18022 |
NCBI Accession | NM_008685, NP_032711 |
UniProt | Q07279 |
Application Notes | Optimal working dilution should be determined by the investigator. |
Restrictions | For Research Use only |
Format | Lyophilized |
Reconstitution | Add 100?μL of sterile PBS. Final peptide concentration is 1?mg/mL in PBS. |
Concentration | 1 mg/mL |
Buffer | Final peptide concentration is 1 mg/mL in PBS. |
Handling Advice | Avoid repeat freeze-thaw cycles. |
Storage | -20 °C |
Storage Comment | For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |