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  • 產(chǎn)品名稱:RetinalGProteinCoupledReceptor(RGR)(C-Term)Peptide

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簡單介紹:
RetinalGProteinCoupledReceptor(RGR)(C-Term)Peptide
詳情介紹:
Blocked Antibody anti-RGR antibody (Retinal G Protein Coupled Receptor) (C-Term) (ABIN2789477)
Sequence GKSGHLQVPA LIAKMVPTIN AINYALGNEM VCRGIWQCLS PQKREKDRTK
Characteristics This is a synthetic peptide designed for use in combination with anti-RGR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively).

Alias Symbols: RP44

Protein Interaction Partner: KIAA1279,RDH5,KIAA1279

Protein Size: 253
Molecular Weight 28 kDa
Gene ID 5995
NCBI Accession NM_001012722, NP_001012740
Research Area Neurology
Application Notes Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100?μL of sterile PBS. Final peptide concentration is 1?mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.