產(chǎn)品詳情

  • 產(chǎn)品名稱：CALCOCO1(CalciumBindingand1)(N-Term)Peptide

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  • 產(chǎn)品廠商：半導(dǎo)體
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簡單介紹：
CALCOCO1(CalciumBindingand1)(N-Term)Peptide
詳情介紹：
Blocked Antibody anti-Calcium Binding and Coiled-Coil Domain 1 (CALCOCO1) (N-Term) antibody (ABIN2787240)
Sequence ESTTDGSPIH TSVQFQASYL PKPGAQLYQF RYVNRQGQVC GQSPPFQFRE
Characteristics This is a synthetic peptide designed for use in combination with anti-CALCOCO1 Antibody(ARP57483_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background CALCOCO1 functions as a coactivator for aryl hydrocarbon and nuclear receptors (NR).CALCOCO1 is recruited to promoters through its contact with the N-terminal basic helix-loop-helix-Per-Arnt-Sim (PAS) domain of transcription factors or coactivators, such as NCOA2. During ER-activation CALCOCO1 acts synergistically in combination with other NCOA2-binding proteins, such as EP300, CREBBP and CARM1. CALCOCO1 is involved in the transcriptional activation of target genes in the Wnt/CTNNB1 pathway. CALCOCO1 functions as a secondary coactivator in LEF1-mediated transcriptional activation via its interaction with CTNNB1. Coactivator function for nuclear receptors and LEF1/CTNNB1 involves differential utilization of two different activation regions.

Alias Symbols: Cocoa, KIAA1536, PP13275, calphoglin

Protein Interaction Partner: APTX,CREBBP,CRYBA2,CTNNBL1,CYTH3,EP300,FOSL1,IPP,KRT15,MAPK1,NDC80,SH3GL3,TBC1D17,MAPK1,CRYBA2,CYTH3,FOSL1,KRT15,NDC80,SH3GL3,TBC1D17

Protein Size: 691
Molecular Weight 77 kDa
Gene ID 57658
NCBI Accession NM_020898, NP_065949
UniProt Q9P1Z2
Application Notes Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100?μL of sterile PBS. Final peptide concentration is 1?mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.