Purpose
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Y-27632 2HCl is a selective ROCK1 (p160ROCK) inhibitor with Ki of 140 nM in a cell-free assay, exhibits >200-fold selectivity over other kinases, including PKC, cAMP-dependent protein kinase, MLCK and PAK.
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Characteristics
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Target: ROCK inhibitor, Autophagy activator Receptor: ROCK1/2, Autophagy
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Purification
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All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
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Purity
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98?%
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Formula
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C14H21N3O
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Solubility
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H2O (100 mM) or PBS (100 mM)
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