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  • 產(chǎn)品名稱：AZ5104

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  • 產(chǎn)品廠商：TargetMol
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AZ5104
詳情介紹：
Purpose AZ5104, the demethylated metabolite of AZD-9291, is a potent EGFR inhibitor with IC50 of <1 1="" 6="" 25="" nm,="" and="" nm="" for="" egfr="" (l858r="" t790m),="" (l858r),="" (l861q),="" (wildtype),="" respectively.="" phase="" 1.="" <="" td="">
Characteristics Target: EGFR inhibitor, IGF-1R inhibitor, TGF-beta/Smad inhibitor
Receptor: EGFR,ErbB4,ACK1,BLK,BRK,MNK2,IGF-1R, ALK,TEC,FES,Ins R
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 99?% +
Formula C27H31N7O2
Solubility 200 mM in DMSO
Molecular Weight 485.58 g/mol
CAS-No 1421373-98-9
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months