產(chǎn)品詳情
簡單介紹:
Telmisartan
詳情介紹:
Purpose | Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to a reduction in arterial blood pressure. Recent studies suggest that telmisartan may also have PPAR-gamma agonistic properties that could potentially confer beneficial metabolic effects. |
Characteristics |
Tradename: MICARDIS Source of Compound: synthetic, BIBR-277 SE Target: RAAS inhibitor, ACE inhibitor, PPAR agonist Receptor: ACE,PPAR gamma Status: USAN, INN, BAN |
Purification | All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality. |
Purity | 98?% |
Formula | C33H30N4O2 |
Solubility | DMSO 13 mg/mL,Water <1 mg="" ml="" <="" td=""> 1> |
Molecular Weight | 514.62 g/mol |
CAS-No | 144701-48-4 |
Application Notes | Optimal working dilution should be determined by the investigator. |
Restrictions | For Research Use only |
Format | Solid |
Storage | -20 °C |
Storage Comment |
For the majority of compounds, they could be dissolved in DMSO or other organic solvent. Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience. Several freeze/thaw cycles should not damage the activity of our small molecule products. However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours. |
Expiry Date | 24 months |