產(chǎn)品詳情

  • 產(chǎn)品名稱：Doxazosinmesylate

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  • 產(chǎn)品廠商：TargetMol
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Doxazosinmesylate
詳情介紹：
Purpose Doxazosin Mesylate is a selective, long-lasting antagonist of α1-adrenergic receptor. Doxazosin Mesylate has been reported to potentiate contraction response to 5-HT in a dose-dependent manner. Doxazosin significantly reduced alcohol drinking and increased water intake in ***** male P rats.Studies has indicated that doxazosin could inhibit TNF-α expression in LPS-induced systemic inflammation model as well as reduce the MCP-1 production in LPS-induced pulmonary inflammation model. Additionally, Doxazosin decreased thickness of footpad in the delayed-type hypersensitivity mice model. Doxazosin had been reported to slightly reduce MCP-1 level in the peritoneal cavity of mice induced by thioglycollate.
Characteristics Tradename: CARDURA
Source of Compound: synthetic, UK-33274-27
Target: Adrenergic Receptor agonist
Receptor: Adrenergic Receptor
Status: USAN, INN, BAN, JAN
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 98?%
Formula C24H29N5O8S
Solubility Freely soluble in DMSO
Molecular Weight 547.58 g/mol
CAS-No 77883-43-3
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months