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  • 產(chǎn)品名稱：FR180204

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  • 產(chǎn)品廠商：TargetMol
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FR180204
詳情介紹：
Purpose FR180204 is a potent and selective ATP-competitive inhibitor of ERK1 and ERK2 with Ki value of 0.31 uM and 0.14 uM respectively, has IC50 values of 0.51 and 0.33 μM in enzymatic assays against ERK1 and ERK2, respectively.
Characteristics Target: ERK inhibitor
Receptor: ERK1/2
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 98?%
Formula C18H13N7
Solubility 100 mM in DMSO
Molecular Weight 327.34 g/mol
CAS-No 865362-74-9
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months
Product cited in: Lv, Zeng, Zhao, Cheng, Zhang, Cai, Hu, Chen: "Cdc42 regulates LPS-induced proliferation of primary pulmonary microvascular endothelial cells via ERK pathway." in: Microvascular research, Vol. 109, pp. 45-53, 2016 (PubMed).