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  • 產(chǎn)品名稱：AT-7519hydrochloride

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  • 產(chǎn)品廠商：Biovision
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AT-7519hydrochloride
詳情介紹：
Purpose A potent CDK inhibitor
Characteristics AT-7519 is a potent CDK inhibitor with potential antineoplastic activity. AT-7519 displays potent antiproliferative activity (40-940 nM) in a panel of human tumor cell lines, and the mechanism of action is shown to be consistent with the inhibition of CDK1 and CDK2 in solid tumor cell lines. AT-7519 causes cell cycle arrest followed by apoptosis in human tumor cells and inhibits tumor growth in human tumor xenograft models.
Purity ≥ 98?% by HPLC
Chemical Name N-(4-Piperidinyl)-4-(2,6-dichlorobenzoylamino)-1H-pyrazole-3-carboxamide hydrochloride
Formula C??H??Cl?N?O?
Permeability Cell-permeable
Solubility DMSO
Molecular Weight 418.71 g/mol
CAS-No 902135-91-5
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and moisture
Storage -20 °C
Expiry Date 36 months