產(chǎn)品詳情

  • 產(chǎn)品名稱：LY-2584702

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
LY-2584702
詳情介紹：
Characteristics

PubChem CID: 46205871
Molecular Formula: C??H??F?N?O?S
Cell Premeable: Yes

LY-2584702 is a potent, ATP-competitive inhibitor of p70S6K signaling, with potential antineoplastic activity. LY-2584702 inhibits ribosomal protein S6 Kinase (p70S6K), and prevents phosphorylation of the S6 subunit of ribosomes, thereby inhibiting normal ribosomal function within tumor cells leading to a decrease in protein synthesis and in cellular proliferation.

Smiles: CC1=CC=C(C=C1)S(=O)(=O)O.CN1C=C(N=C1C2CCN(CC2)C3=NC=NC4=C3C=NN4)C5=CC(=C(C=C5)F)C(F)(F)F

InChi: InChI=1S/C21H19F4N7.C7H8O3S/c1-31-10-17(13-2-3-16(22)15(8-13)21(23,24)25)29-19(31)12-4-6-32(7-5-12)20-14-9-28-30-18(14)26-11-27-20
1-6-2-4-7(5-3-6)11(8,9)10/h2-3,8-12H,4-7H2,1H3,(H,26,27,28,30)
2-5H,1H3,(H,8,9,10)

Inchi Key: HDYUXDNMHBQKAU-UHFFFAOYSA-N
Purity ≥ 98?% by HPLC
Chemical Name 4-[4-[4-[4-fluoro-3-(trifluoromethyl)phenyl]-1-methyl-imidazol-2-yl]-1-piperidyl]-1H-pyrazolo[3,4-d]pyrimidine
Formula C??H??F?N?O?S
Permeability Cell-permeable
Background Synonyms: 4-[4-[4-[4-fluoro-3-(trifluoromethyl)phenyl]-1-methyl-imidazol-2-yl]-1-piperidyl]-1H-pyrazolo[3,4-d]pyrimidine
Molecular Weight 617.62 g/mol
CAS-No 1082949-68-5
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 36 months