產(chǎn)品詳情

  • 產(chǎn)品名稱：Torcetrapib

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
Torcetrapib
詳情介紹：
Characteristics Torcetrapib is a cholesteryl ester transfer protein (CETP) inhibitor (IC50= 37 nM). It raises high-density lipoprotein (HDL) cholesterol and reduces low-density lipoprotein (LDL) cholesterol levels. However, in clinical trials, Torcetrapib displayed unfavorable off-target effects in cardiovascular system. PDGFR, HGFR (c-Met), IL-2 receptor, and ErbB1- tyrosine kinase have subsequently been identified as direct off-targets of this compound.
Purity ≥ 98?%
Chemical Name (2R,4S)-ethyl 2-ethyl-4-(methoxycarbonyl)-6-(trifluoromethyl)-3,4-dihydroquinoline-1(2H)-carboxylate; CP-529414, CP529414, CP 529414
Formula C??H??F?N?O?
Permeability Cell-permeable
Molecular Weight 600.47 g/mol
CAS-No 262352-17-0
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and air
Storage -20 °C
Expiry Date 36 months
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image for Torcetrapib (ABIN1685851) Torcetrapib