產(chǎn)品詳情

  • 產(chǎn)品名稱：HeptelidicAcid

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  • 產(chǎn)品廠商：Biovision
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HeptelidicAcid
詳情介紹：
Characteristics A sesquiterpene antibiotic, isolated from Trichoderma sp. A potent and selective glyceraldehyde 3-phosphate dehydrogenase (GAPDH) inhibitor. Binds to the essential Cys149 residue in the catalytic site of GAPDH. Selectively kills high-glycolytic cancer cells through glucose-dependent active ATP deprivation. Selective and competitive inhibitor of mammalian DNA polymerases beta, lambda and terminal deoxynucleotidyl transferase (TdT) in family X of pols.
Synonyms: Koningic acid, Avocettin, FO-4443, BRN 5091359
Purity 95?% by HPLC
Chemical Name Koningic acid; Avocettin; FO-4443; BRN 5091359
Formula C??H??O?
Permeability Cell-permeable
Molecular Weight 280.32 g/mol
CAS-No 74310-84-2
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
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