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  • 產(chǎn)品名稱:Robotnikinin

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  • 產(chǎn)品廠商:Biovision
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Robotnikinin
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Characteristics A small-molecule chemical inhibitor of Sonic hedgehog (Shh) signaling, that blocks hedgehog signaling through specific binding and blockade of Shh signaling factor. It is the first-characterized hedgehog inhibitor whose molecular mechanism of action is through blockade of Shh protein and not a subsequent factor of the hedgehog signaling cascades. Robotnikinin binds to the Shh-N terminal protein in a concentration-dependent fashion with a kDaof 9 μM.
Purity ≥ 97?% by NMR
Chemical Name N-[(4-Chlorophenyl)methyl]-2-[(2R,6S,8E)-5, 12-dioxo-2-phenyl-1-oxa-4-azacyclododec-8-en-6-yl]acetamide
Formula C??H??ClN?O?
Permeability Cell-permeable
Molecular Weight 454.95 g/mol
Research Area Kinases/Phosphatases
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and air
Storage -20 °C
Expiry Date 36 months
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 image for Robotnikinin (ABIN629318) Robotnikinin