產(chǎn)品詳情

  • 產(chǎn)品名稱：ManumycinA

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
ManumycinA
詳情介紹：
Characteristics An antibiotic Isolated from Streptomyces parvulus. A Potent, selective and competitive cell permeable rasfarnesyltransferase (FTase) inhibitor (IC50= 30 nM). Does not affect geranylgeranyltransferase (GGTase) (IC50= 180 μM). Blocks insulin-induced MAP kinase activation in rat cardiac myocytes (19 μM).μM). Inhibition is competitive with respect to farnesyl pyrophosphate and non-competitive with respect to Ras.
Purity ≥ 96?% by HPLC
Chemical Name NSC-622141; UFC 1C
Formula C??H??N?O
Permeability Cell-permeable
Molecular Weight 550.64 g/mol
CAS-No 52665-74-4
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 36 months
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image for Manumycin A (ABIN1685689) Manumycin A