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  • 產品名稱:CUDC-101

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簡單介紹:
CUDC-101
詳情介紹:
Characteristics A potent multitargeted inhibitor of histone deacetylase (HDAC) and the receptor kinases epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), with IC50 values of 4.4, 2.4, and 15.7 nM, respectively. Displays potent antiproliferative and proapoptotic activities against cultured and implanted tumor cells that are sensitive or resistant to several approved single-targeted drugs.
Purity ≥ 98?% by HPLC
Chemical Name 7-((4-((3-ethynylphenyl)amino)-7-methoxyquinazolin-6-yl)oxy)-N-hydroxyheptanamide
Formula C??H??N?O?
Permeability Cell-permeable
Molecular Weight 434.49 g/mol
CAS-No 1012054-59-9
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and air
Storage -20 °C
Expiry Date 48 months
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