產(chǎn)品詳情

  • 產(chǎn)品名稱：Chelerythrinechloride

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡單介紹：
Chelerythrinechloride
詳情介紹：
Characteristics Cell-permeable. A selective protein kinase C (PKC) inhibitor (IC50 =0.66 μM). Chelerythrine is at least 100-fold more selective for PKCs than for other kinases. It induces apoptotic cell death in polymorphonuclear leukocyte through activation of caspase-3. In addition, Chelerythrine treated cells underwent apoptosis, with features that suggest involvement of the mitochondrial pathway, and through a mechanism that involves inhibition of the anti-apoptotic inhibitor BclXL.
Synonyms: 1,2-Dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridinium chloride
Purity ≥ 98?% by HPLC
Chemical Name 1,2-Dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridinium chloride
Formula C??H??NO?Cl
Permeability Cell-permeable
Molecular Weight 383.82 g/mol
CAS-No 3895-92-9
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
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