產(chǎn)品詳情

  • 產(chǎn)品名稱：Erastin

  • 產(chǎn)品型號(hào)：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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Erastin
詳情介紹：
Characteristics Erastin is a selective antitumor agent that displays greater lethality in human tumour cells harbouring mutations in the oncogenes HRAS, KRAS or BRAF. It binds to mitochondrial volatage-dependent anion channels (VDAC) proteins, more specifically on VDAC2 and alters its gating. Erastin rapidly induces an oxidative, non-apoptotic cell death in several human tumors harboring activating mutations in the RAS-RAF-MEK signaling.
Purity ≥ 98?% by HPLC
Chemical Name 2-[1-[4-[2-(4-Chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-Quinazolinone
Formula C??H??ClN?O?
Permeability Cell-permeable
Molecular Weight 547.04 g/mol
CAS-No 571203-78-6
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and moisture
Storage -20 °C
Expiry Date 24 months
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