產(chǎn)品詳情
簡單介紹:
A771726
詳情介紹:
Characteristics | Physiologically active metabolite of the immunosuppressive drug leflunomide. Inhibits the activity of dihydrorotate dehydrogenase and of protein tyrosine kinases. Blocks TNF-mediated NF-kappaB activation in a dose- and time-dependent manner. Also inhibits the activity of COX-2 in vitro and in vivo. |
Purity | ≥ 98?% by HPLC |
Chemical Name | N-(4-Trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide, 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide |
Formula | C??H?F?N?O? |
Permeability | Cell-permeable |
Molecular Weight | 270.21 g/mol |
CAS-No | 108605-62-5 |
Restrictions | For Research Use only |
Format | Solid |
Handling Advice | Protect from light and air |
Storage | -20 °C |
Expiry Date | 48 months |
Supplier Images |
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