產(chǎn)品詳情

  • 產(chǎn)品名稱：Flavopiridol

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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Flavopiridol
詳情介紹：
Characteristics Cell-permeable. Flavopiridol is a synthetic flavonoid compound used as an anticancer agent. It is a serine/threonine kinase inhibitor that broadly targets cyclin-dependent kinases (CDKs), including the cyclin 9/cyclin T complex (pTEF-b), preventing activation of RNA polymerase II. Flavopiridol initiates cell cycle arrest and p53-independent apoptosis through down-regulation of Mcl-1 and X-linked inactivator of apoptosis (XIAP).
Synonyms: 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-4-chromenone, HMR 1275, L86-8275, NSC 649890
Purity ≥ 98?% by HPLC
Chemical Name 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-4-chromenone; HMR 1275; L86-8275; NSC 649890
Formula C??H??ClNO?
Permeability Cell-permeable
Molecular Weight 401.84 g/mol
CAS-No 146426-40-6
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light
Storage -20 °C
Expiry Date 24 months
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