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  • 產(chǎn)品名稱:TAMEHydrochloride

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  • 產(chǎn)品廠商:Biovision
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TAMEHydrochloride
詳情介紹:
Characteristics A small molecule anaphase-promoting complex/cyclosome (APC/C) inhibitor that stabilizes APC/C substrates in mitotic Xenopus extracts. TAME binds to APC and prevents its activation by Cdc20 and Cdh1. In the absence of APC substrates, TAME ejects Cdc20 from the APC by promoting Cdc20 autoubiquitination in its N-terminal region. TAME also stabilizes cyclin B1 by prematurely terminating ubiquitination.
Synonyms: N-p-Tosyl-L-arginine methyl ester hydrochloride
Purity ≥ 98?% by TLC
Chemical Name N-p-Tosyl-L-arginine methyl ester hydrochloride
Formula C??H??N?O?S.HCl
Permeability Not-permeable
Molecular Weight 378.87 g/mol
CAS-No 1784-03-8
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 24 months
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