產(chǎn)品詳情
簡單介紹:
Emetinedihydrochloride
詳情介紹:
Characteristics | A bitter-tasting crystalline alkaloid,derived from ipecac root and used in the treatment of amebiasis and as an emetic.Irreversibly blocks protein synthesis by inhibiting the movement of ribosome along the mRNA. Induces hypotension by blocking adrenoreceptors. Inhibits DNA replication in the early S phase. Inhibits HIF-1 activation by hypoxia. Induces apoptosis in leukemia cells. Also, selectively inhibits multiple glioblastoma (GBM) stem cells-enriched cultures. |
Purity | ≥ 98?% by titration |
Chemical Name | 2S,3R,11bS)-2-{[(1R)-6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl}-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinoline |
Formula | C??H??N?O??2HCl |
Permeability | Not-permeable |
Molecular Weight | 553.56 g/mol |
CAS-No | 316-42-7 |
Restrictions | For Research Use only |
Format | Solid |
Handling Advice | Protect from light and moisture |
Storage | 4 °C |
Expiry Date | 48 months |
Supplier Images |
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