產(chǎn)品詳情
簡單介紹:
Necrostatin-1
詳情介紹:
Characteristics | Inhibits necroptosis, a non-apoptotic cell death pathway. Does not inhibit FAS-induced apoptosis and has no effect on apoptotic morphology. Inhibits RIP1 kinase, the key upstream kinase involved in the activation of necroptosis (EC50 = 180 nM). |
Purity | ≥ 98?% by TLC |
Chemical Name | 5-(1H-Indol-3-ylmethyl)-3-methyl-2-thioxo-4-imidazolidinone; Methylthiohydantoin-DL-tryptophan; Nec-1 |
Formula | C??H??N?OS |
Permeability | Cell-permeable |
Molecular Weight | 259.33 g/mol |
CAS-No | 4311-88-0 |
Research Area | Kinases/Phosphatases |
Restrictions | For Research Use only |
Format | Solid |
Handling Advice | Protect from air and light |
Storage | -20 °C |
Expiry Date | 24 months |
Supplier Images |
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