產(chǎn)品詳情

  • 產(chǎn)品名稱：EZSolution?TAPI-1

  • 產(chǎn)品型號：
  • 產(chǎn)品廠商：Biovision
  • 產(chǎn)品文檔：
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簡單介紹：
EZSolution?TAPI-1
詳情介紹：
Purpose Inhibits TACE and other metalloproteases.
Brand EZSolution?
Characteristics Molecular formular: C26H37N5O5
Purity ≥ 95?% by HPLC
Chemical Name N-(R)-(2-(Hydroxyaminocarbonyl)methyl)-4-methylpentanoyl-L-naphthylalanyl-L-alanine amide; TNF protease inhibitor-0; C1
Formula C??H??N?O?
Permeability Not-permeable
Molecular Weight 499.3 g/mol
CAS-No 171235-71-5
Comment

Synonyms:
N-(R)-(2-(Hydroxyaminocarbonyl)methyl)-4-methylpentanoyl-L-naphthylalanyl-L-alanine amide, TNF protease inhibitor-0, C1
Inhibitor of TNF- processing (IC = 100 nM), similar to TAPI-0 (Cat. No. 2067-1), but more stable in tissue culture and in vivo. Inhibits TACE and other metalloproteases. Blocks release of TNF- (IC = 50-100 M), APP (1-8 M), IL6R (5- 10 M), TNFRI (5 -10 M), TNFRII (25 -50 M), and ObRa (leptin receptor), but not CSF-1, from cells in culture
Restrictions For Research Use only
Format Liquid
Concentration 10 mM
Buffer anhydrous DMSO
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 12 months
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